Peptide Reality Check

Evidence-graded guide to popular peptides: which ones work, which don't, the clinical data, risks, studied doses, and Dr. Alex Tatem's tier grades with links to his videos.

• Retatrutide — S
• Tirzepatide — S
• Semaglutide — S
• Growth hormone — S
• GHK-Cu — A
• Tesamorelin — B
• IGF-1 LR3 — B
• BPC-157 — C
• TB-500 — C
• KPV — not graded
• CJC-1295 — C
• Ipamorelin — D
• Sermorelin — not graded
• MK-677 — S
• PT-141 — S
• hCG — S
• Kisspeptin — D
• MOTS-c — D
• NAD+ — B
• SS-31 — not graded
• Semax — B
• Selank — B
• AOD-9604 — F
• Epitalon — F
• Glow stack — C
• Methylene blue — F
• Melanotan I & II — S
• GHRP-2 & GHRP-6 — C
• Mazdutide — A
• Adipotide — F
• DSIP — C
• Dihexa — F
• 5-Amino-1MQ — C
• SLU-PP-332 — C
• Insulin (non-diabetic use) — F